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When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. The R34 Rule, also known as "Rule 34," is an internet adage that states, "If it exists, there is porn of it. Thus, criteria in research protocols that target or exclude certain populations are warranted where nondiscriminatory justifications establish that such criteria are appropriate with respect to the health or safety of the subjects, the scientific study design, or the purpose of the research. Required: Only accepting applications that propose clinical trial s.
